Myristoyl Pentapeptide-17: Eyelash and Eyebrow Enhancing Peptide
Myristoyl Pentapeptide-17 (CAS 959610-30-1) is a lipopeptide specifically developed for eyelash and eyebrow enhancement through keratin gene expression stimulation. The myristoyl fatty acid chain provides targeted delivery to hair follicle keratinocytes, while the pentapeptide sequence activates keratin biosynthesis pathways critical for lash fiber growth and thickness. TCS NEXUS S.L. supplies Myristoyl Pentapeptide-17 from our warehouse in Valencia, Spain.
Mechanism of Action
Myristoyl Pentapeptide-17 targets the matrix cells of the hair follicle bulb, where active keratin synthesis occurs during the anagen (growth) phase. The myristoyl (C14) lipid chain anchors the peptide into follicular cell membranes, positioning the bioactive pentapeptide sequence for receptor interaction. Once internalized, the peptide upregulates expression of type II hair keratins (K85 and K86) and keratin-associated proteins (KAPs) that determine lash fiber diameter, tensile strength, and overall length. Additionally, the peptide extends the anagen phase duration by modulating dermal papilla signaling, allowing individual lash fibers to achieve greater length before entering the catagen transition.
Clinical Results
In a 12-week clinical study, Myristoyl Pentapeptide-17 at 200ppm applied twice daily via a lash serum formulation increased eyelash length by 25% compared to baseline measurements. Digital macro-photography and image analysis confirmed the length gains, while lash density (number of visible lashes per 4mm segment) increased by 15%. Lash fiber thickness, measured by optical coherence tomography, improved by 12%. Subjects reported noticeable improvements in lash fullness and length from week 6 onward, with continued progressive enhancement through the study endpoint.
Formulation Guidelines
Myristoyl Pentapeptide-17 is recommended at 100-300ppm in finished lash and brow enhancing products. Due to the myristoyl chain, the peptide has amphiphilic characteristics and disperses readily in both aqueous and oil-in-water emulsion systems. Optimal delivery vehicles include low-viscosity serums applied with mascara-type applicators, brow gels, and overnight lash conditioning treatments. Cosmetic chemists frequently combine Myristoyl Pentapeptide-17 with biotin, panthenol, and biotinoyl tripeptide-1 for comprehensive lash nourishment addressing both keratin synthesis and follicle conditioning pathways.
Product Development Applications
- Eyelash growth serums with brush or wand applicators
- Eyebrow conditioning and densifying treatments
- Lash-enhancing mascaras with peptide-fortified formulas
- Overnight lash repair and strengthening balms
- Multi-peptide lash systems combined with Biotinoyl Tripeptide-1
European Supply and Quality Assurance
TCS NEXUS S.L. operates as a dedicated Myristoyl Pentapeptide-17 supplier in Europe with vertically integrated peptide synthesis from our warehouse in Valencia, Spain. Each production batch is tested by HPLC for purity, LC-MS for molecular identity, and microbiological screening for cosmetic safety compliance. Full documentation includes Certificate of Analysis, MSDS, and regulatory documentation for natural cosmetic positioning.
Ordering Information
Evaluation quantities start from 1g for initial formulation development and stability testing in lash serum prototypes. Production orders begin at 100g with volume pricing for brands scaling lash-care product lines. Standard EU delivery is completed within 3-5 business days. Contact our peptide application team for guidance on optimal delivery systems and concentration ranges for your specific lash or brow enhancement product concept.
Technical Support and Samples
Request COA documents, sample availability, or support for custom synthesis.
Frequently Asked Questions
Do you provide COA documents for Myristoyl Pentapeptide-17 (CAS 959610-30-1) EU?
Yes. Each lot can be supplied with a Certificate of Analysis, HPLC purity data, and relevant quality-control results for technical review.
Are samples available for Myristoyl Pentapeptide-17 (CAS 959610-30-1) EU?
Yes. Sample availability can be confirmed for formulation screening and internal evaluation before a commercial order is placed.
What is the delivery lead time for Myristoyl Pentapeptide-17 (CAS 959610-30-1) EU?
For stocked material in Valencia, EU delivery is typically 5 to 7 business days. Final timing depends on destination and requested volume.
Do you also support custom synthesis and technical inquiries?
Yes. The team can help with custom synthesis, raw-material selection, technical documentation, and supply planning.