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Linaclotide_Other_Varieties

Linaclotide_Other_Varieties

Name:Linaclotide

Indication:Constipated irritable bowel syndrome,chronic idiopathic constipation

CAS No.:851199-59-2

Molecular formula:C59H79N15O21S6

Linaclotide, (sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere)[2] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.[3][4] It has a black box warning about the risk of serious dehydration in children in the US; the most common adverse effects in others are gastrointestinal.[3]

It is an oligo-peptide agonist of guanylate cyclase 2C and remains in the GI tract after it is taken orally. It was approved in the US and Europe in 2012.[5]

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