Indication:Hereditary angioedema in C1-esterase-inhibitor deficiency

CAS No.:30308-48-4

Molecular formula:C59H89N19O13S

Icatibant, sold under the brand name Firazyr, is a medication for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency.[4][2][3] It is not effective in angioedema caused by medication from the ACE inhibitor class.[5]

It is a peptidomimetic consisting of ten amino acids, which is a selective and specific antagonist of bradykinin B2 receptors. It cost about US$8,000 to 9,000 per dose as of 2014.[6][7]

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